The Best Vagus Nerve Stimulator? Comparing NeoRhythm to Nurosym, Gammacore, Pulsetto, and Sensate

Vagus nerve stimulation (VNS) has gained traction as a non-invasive therapy for enhancing overall well-being. While several devices claim to offer effective VNS, not all are created equal. Here, we compare NeoRhythm with four other prominent VNS devices: Nurosym, Gammacore, Pulsetto, and Sensate, based on key criteria like scientific validation, effectiveness, safety, and cost.

Note: This blog is a result of extensive research and analysis of existing online content. Many online comparisons are artificially generated and may not provide a fair or honest assessment. A series of very similar blogs have been published comparing vagus nerve stimulators, often with biased perspectives. It is important to rely on verifiable scientific data rather than misleading marketing claims.

Marko Kadunc, CEO

NeoRhythm vs. Competitors: What Sets It Apart?

1. Scientific Validation

NeoRhythm stands out with a published study in Bioelectromagnetics, one of the most rigorous scientific journals. This validation provides a strong foundation for its efficacy. Additionally, NeoRhythm has two extra studies further supporting its effectiveness in relaxation and attention enhancement, other studies are available on research page.

• Nurosym & Gammacore: Supported by multiple scientific studies, including randomized controlled trials. (check Nurosym & Gammacore science behind page)
• Pulsetto & Sensate: Have not yet published peer-reviewed studies specific to their devices. Pulsetto uses electrical stimulation applied to the neck to engage the vagus nerve. While electrical stimulation is a common method for VNS, Pulsetto has not yet published peer-reviewed studies confirming its specific effectiveness and safety. (check Pulsetto and Sensate  science behind page)

✅ Key takeaway : NeoRhythm, Nurosym, and Gammacore (scientifically validated)

2. Method of Stimulation

NeoRhythm uses PEMF (Pulsed Electromagnetic Field) therapy, a non-invasive and completely natural method that stimulates the vagus nerve using biologically recognizable pulses.

• Nurosym & Gammacore: Use electrical stimulation, which may require gel application and could feel more intense for some users.
• Pulsetto: Pulsetto: Uses electrical stimulation and requires the application of conductive gel for proper function, but research on its specific approach is still limited.
• Sensate: Uses vibration-based stimulation, which may promote relaxation but lacks direct evidence of vagus nerve activation.

✅ Key takeaway : NeoRhythm (safe, natural, and gel-free stimulation)

3. Safety & Wearable Status

NeoRhythm is a completely natural solution with no known side effects. Unlike electrical-based devices, it does not require electrodes or direct nerve contact.

• Nurosym & Gammacore: Certified wearable devices that have undergone scientific safety evaluations.
• Pulsetto: Does not have extensive safety studies available yet. Check Pulsetto science behind page.
• Sensate: Uses vibration, which is generally well tolerated, though not a direct form of VNS.

✅ Key takeaway : NeoRhythm, Nurosym, and Gammacore (safe and certified devices)

4. Whole-Body Benefits

NeoRhythm is unique as it can be used as a whole-body device, promoting relaxation, cognitive function, and sleep improvement.

• Nurosym: Designed to target the ear for vagus nerve activation.
• Gammacore: Primarily used for headache relief via neck application.
• Pulsetto: Applied to the neck.
• Sensate: Placed on the chest and designed for relaxation rather than direct vagus nerve activation.

✅ Key takeaway : NeoRhythm (versatile for whole-body applications)

5. Cost Comparison – How much do I spend in 5 years. 

NeoRhythm offers the best price-to-performance ratio among all the competitors.

• NeoRhythm: One-time purchase, competitively priced at €299.
• Nurosym: €699, higher initial investment but no recurring fees.
• Gammacore: €2,079 for the first year, with ongoing costs for refills.
• Pulsetto: €250, but includes a paid app subscription and gel
• Sensate: €277, additional app costs over time.

✅ Key takeaway : NeoRhythm (affordable with no recurring fees)

Device Descriptions

NeoRhythm

NeoRhythm is a science-backed, gel-free, and cost-effective VNS solution that offers natural vagus nerve stimulation without the risks associated with high-intensity electrical devices. It provides a holistic, whole-body approach that other competitors lack, making it an ideal choice for those looking for a safe, non-invasive, and effective way to enhance their well-being.

Nurosym

Nurosym is a CE-marked vagus nerve stimulator that utilizes auricular vagal neuromodulation therapy (AVNT) to deliver precise electrical pulses to the vagus nerve via the ear. With over 40 peer-reviewed studies supporting its effectiveness, it is widely used for nervous system regulation. However, its higher cost and recurring expenses may be a consideration for long-term use.

Gammacore

Gammacore is a non-invasive vagus nerve stimulator designed primarily for migraine and headache relief. It delivers electrical stimulation to the cervical vagus nerve via the neck. While it has strong clinical backing, its cost structure includes significant recurring expenses, making it one of the more expensive options over time.

Pulsetto

Pulsetto is a wearable VNS device that stimulates the vagus nerve through bilateral electrical pulses applied to the neck. It requires the use of conductive gel for proper operation and is controlled via a mobile app. While marketed as a relaxation and stress-management tool, it currently lacks peer-reviewed research validating its long-term efficacy and safety.

Sensate

Sensate is a relaxation-focused device that uses sound and vibration to promote stress relief, claiming to indirectly stimulate the vagus nerve. Unlike other VNS devices, Sensate does not provide direct electrical stimulation. While it may offer relaxation benefits, it lacks clinical validation as a true vagus nerve stimulator.

1. Scientific Comparison of the 4 Vagus Nerve Stimulators – Nurosym, Gammacore, Pulsetto, Sensate (LINK)

2. We’ve Tested 5 Devices In 5 Months. Which Vagus Nerve Stimulator Is Currently #1 on the Market? (LINK)

3. Omnipemf research page (LINK)