Memorial Day Offer

Discover your mystery discount!

Sleep disorder

Causes of Sleep Disorders: – CDC recommendations for sleep decrease with age – Good sleep quality essential to avoid disorders – Traumatic childhood experiences increase […]

« Back to Glossary Index

Causes of Sleep Disorders:
– CDC recommendations for sleep decrease with age
– Good sleep quality essential to avoid disorders
– Traumatic childhood experiences increase risk for disorders
– Idiopathic REM sleep behavior disorder may be hereditary
– Traumatic brain injury linked to narcolepsy and apnea

Sleep Disorders and Neurodegenerative Diseases:
– Neurodegenerative diseases often linked to sleep disorders
– PD patients commonly experience insomnia and hypersomnia
– RBD precursor for neurodegenerative diseases
– Brain impairment disrupts sleep and wakefulness
– Sleep disturbances worsen cognitive functioning

Sleep Disturbances and Alzheimer’s Disease:
– 45% of AD patients experience sleep disturbances
– Insomnia and hypersomnia common in AD
– Changes in sleep architecture observed in AD
– Sleep fragmentation and reduced REM sleep in AD
– Circadian rhythm disruption leads to sleep disturbances

Management and Treatment of Sleep Disorders:
– Polysomnography and actigraphy commonly used for diagnosis
– Sleep disruptions can be caused by various issues
– Management of secondary sleep disturbances focuses on underlying conditions
– Lack of awareness of children with sleep disorders
– Common factors in onset of sleep disorders include medication use and stress

Prevention, Research, and Impact on Neurological Health:
– More research needed on hereditary nature of sleep disorders
– Population susceptible to sleep disorders includes TBI survivors
– Limited research on relationship between sleep disorders and neurodegenerative disease
– Sleep disturbances negatively impact quality of life
– Understanding relationship between sleep disorders, AD, and neurological health is crucial

Glymphatic Clearance, AB Burden, and NREM Sleep:
– Glymphatic clearance is responsible for removing AB burden
– Sleep reduces AB burden by decreasing metabolic activity and oxidative stress
– Aging decreases NREM SWS sleep, leading to increased AB burden and plaque formation

Impact on Hippocampus, Memory, and AD:
– AB plaques initially form in the hippocampus
– Hippocampus cell death occurs due to AB plaques
– Diminished memory performance and cognitive decline are linked to hippocampus cell death
– Memory consolidation crucial for long-term memory occurs during NREM sleep
– Decreased NREM sleep leads to poorer memory consolidation

Relationship Between AD, Sleep Disorders, and Cognitive Decline:
– Development of AD correlates with prominent sleep disorders
– Sleep disorders worsen disease progression in AD
– Sleep disturbances form a bidirectional relationship with AD
– Sleep disturbances exacerbate AD progression
– Cognitive decline in AD is associated with hippocampus cell death

Positive Feedback Loop in AD and Sleep Disorders:
– Sleep disturbances amplify AB plaque formation
– AB plaques initially impact the hippocampus, critical for memory
– Disease progression in AD is worsened by sleep disorders
– The relationship between AD and sleep disorders is bidirectional

Importance of NREM Sleep for Neurological Health:
– NREM sleep is crucial for glymphatic clearance and AB burden reduction
– Memory consolidation, vital for long-term memory, occurs during NREM sleep
– Poor memory consolidation results from decreased NREM sleep
– Hippocampus, integral for memory formation, is impacted by AB plaques

Sleep disorder (Wikipedia)

A sleep disorder, or somnipathy, is a medical disorder of an individual's sleep patterns. Some sleep disorders are severe enough to interfere with normal physical, mental, social and emotional functioning. Sleep disorders are frequent and can have serious consequences on patients' health and quality of life. Polysomnography and actigraphy are tests commonly ordered for diagnosing sleep disorders.

Sleep disorder
A child sits on a hospital bed in pyjamas with soft toys. Along with other measurement devices, the child has electrodes taped to their scalp and face.
Pediatric polysomnography
SpecialtyClinical psychology, Psychiatry, Sleep medicine, Neurology

Sleep disorders are broadly classified into dyssomnias, parasomnias, circadian rhythm sleep disorders involving the timing of sleep, and other disorders including ones caused by medical or psychological conditions. When a person struggles to fall asleep or stay asleep with no obvious cause , it is referred to as insomnia, which is the most common sleep disorder. Others include sleep apnea, narcolepsy and hypersomnia (excessive sleepiness at inappropriate times), sleeping sickness (disruption of sleep cycle due to infection), sleepwalking, and night terrors.

Sleep disruptions can be caused by various issues, including teeth grinding (bruxism) and night terrors. Management of sleep disturbances that are secondary to mental, medical or substance abuse disorders should focus on the underlying conditions.

Primary sleep disorders are common in both children and adults. However, there is a significant lack of awareness of children with sleep disorders, due to most cases being unidentified. Several common factors involved in the onset of a sleep disorder include increased medication use, age-related changes in circadian rhythms, environmental changes, lifestyle changes, pre-diagnosed physiological problems, or stress. Among the elderly, the risk of developing sleep disordered breathing, periodic limb movements, restless legs syndrome, REM sleep behavior disorders, insomnia, and circadian rhythm disturbances is especially increased.

« Back to Glossary Index
This site uses cookies to offer you a better browsing experience. By browsing this website, you agree to our use of cookies.