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Neurodegenerative disease

– Causes of Neurodegenerative Diseases: – Genetic mutations – Environmental factors – Protein misfolding – Oxidative stress – Inflammation – Common Types of Neurodegenerative Diseases: […]

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– Causes of Neurodegenerative Diseases:
– Genetic mutations
– Environmental factors
– Protein misfolding
– Oxidative stress
– Inflammation

– Common Types of Neurodegenerative Diseases:
– Alzheimer’s disease
– Parkinson’s disease
– Huntington’s disease
– Amyotrophic lateral sclerosis (ALS)
– Multiple sclerosis

– Symptoms of Neurodegenerative Diseases:
– Memory loss
– Cognitive decline
– Motor impairment
– Behavioral changes
– Speech difficulties

– Diagnosis of Neurodegenerative Diseases:
– Medical history review
– Physical and neurological examinations
– Imaging tests (MRI, CT scans)
– Blood tests
– Cerebrospinal fluid analysis

– Treatment and Management of Neurodegenerative Diseases:
– Medications (e.g., cholinesterase inhibitors)
– Physical therapy
– Occupational therapy
– Speech therapy
– Supportive care and counseling

Neurodegenerative disease (Wikipedia)

A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, tauopathies, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities suggest that therapeutic advances against one neurodegenerative disease might ameliorate other diseases as well.

Neurodegenerative disease
Normal brain on left contrasted with structural changes shown in brain on right of person with Alzheimer's disease, the most common neurodegenerative disease
SpecialtyNeurology, Psychiatry

Within neurodegenerative diseases, it is estimated that 55 million people worldwide had dementia in 2019, and that by 2050 this figure will increase to 139 million people.

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